Evaluation of Antileishmanial Activities of a Peganum Harmala and Achillea Millefolium Essential oils and their combinations against Leishmania Infantum Promastigotes
نویسندگان
چکیده
Medicinal plants and their derivations are used as safe agents for the treatment of parasitic diseases. This preliminary study investigates antileishmanial activities Peganum harmala essential oil (PHEO), Achillea millefolium oils (AMEO) combinations against Leishmania infantum promastigotes. A standard strain L. promastigote was cultured in a 96-well Novy-MacNeal-Nicolle media culture glucantime, PHEO, AMEO, an equal ratio both 80% PHEO+20%AMEO were investigated concentrations 10, 100, 500 1000 mg/mL interval times 24h, 48h 72h. The results showed that greatest inhibition observed 50PHEO+ AMEO lowest seen control group. increased time concentration significantly efficiencies. analyses significant interaction between [F (10, 360)=7.84, P=0.000]. better effects with time. In sum, combination PHEO its potential structure must be considered future studies.
منابع مشابه
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ژورنال
عنوان ژورنال: Journal of apitheraphy and nature
سال: 2022
ISSN: ['2667-4734']
DOI: https://doi.org/10.35206/jan.1174836